The Pathology of Dirofilariasis in Humans Has Never Been Studied
The pathology in humans has never even been studied. Because there is no test for the disease it is near impossible to know who even has this disease so it is impossible to gather enough patients together to create a proper cohort study of the disease. In fact, nowhere in the published archives is it even identified that an Occult Infection is the default state of the disease in humans. If they can’t even get this fact correct it is quite obvious that nobody has paid any attention to the disease in the human population.
The only detectable manifestation of this disease that can possibly occur prior to a successful occult form of this disease is the cutaneous skin nodule. When a person is bitten and the filaria does not find the incision point it may try to burrow into some other orifice on the surface of the skin and fail to penetrate successfully into the bloodstream. They may become trapped and isolated by the host immune system and be forced to live in this isolated environment sealed off from the host immune system. All other instances become a part of the occult infection first before traveling to any other areas of the body where they might later become visible to a doctor in some way. If its not at the original site of infection then it is part of a successful occult infection.
Can we actually prove there has been no proper study?
Yes. A simple search on Google Scholar with the right search terms will return zero results thus demonstrating that there is a complete lack of any clinical research other than a few token case studies which look only at manifestations of the disease which are visible to a doctor. These cases are a statistically insignificant minority of the total number of infections.
To verify this is in fact the case, go to https://scholar.google.com/ and do a few quick searches.
Enter each set of the following search terms:
“Dirofilaria” “Human” “long term study”
“Dirofilaria” “Human” “cohort”
“Dirofilaria” “Human” “occult” “Study”
Do enter the quotes in the above queries. Each query above will return all the exact matches before any partial matches are returned. After each search result is returned quickly scan those results for any record on that first page that contains every search term you provided. Count them. It’s zero. Feel free to try other search terms as the last parameter just to prove that the search engine is actually working correctly.
So, there are no experts on the topic of Human Dirofilariasis Pathology. Anyone that even claims to understand this disease in humans is simply not telling the truth, because the pathology in humans has never been studied. Out of sight, out of mind. Until there is a clinical test developed for occult infections in humans we will never be able to study this disease properly. There can be no diagnosis, no statistics, and thus no money that is needed to develop a proper clinical research study for this disease. Until that time it is impossible to declare that this disease is not a problem simply due to lack of evidence. If you don’t ever look you will never find it.