The Human Dirofilariasis Research Institute (HDRI)

Human Heartworm Disease – A Debilitating Yet Unrecognized Epidemic

Human heartworm, disease, also known scientifically as Dirofilariasis, is a parasitic infection caused by the filarial worm Dirofilaria immitis or Dirofilaria repens and is primarily transmitted through the bites from infected insects such as mosquitoes. The disease manifests in various forms, including ocular, pulmonary, and subcutaneous infections, but the most common form in humans is the occult infection, wherein the adult worms reside primarily in the vascular system.

This disease is often asymptomatic in humans, making it difficult to diagnose. Yet, with more than 41.1 million Americans potentially exposed, it can lead to chronic health issues, including pulmonary complications, chronic inflammation, immune system suppression, respiratory issues, Formication, and other systemic health problems. The chronic nature of the disease and the lack of medical support can also lead to mental health issues, including anxiety, depression, and even suicide.

Testing & Treatment are Paramount

The long-term effects of this disease can be severe and life-altering. Without proper diagnosis or treatment, it can result in a range of debilitating symptoms that significantly affect the overall quality of life. Currently, there is no approved serological test for diagnosing Dirofilariasis in humans, and treatment options are limited. Please join us in advocating for those suffering alone and unheard.

Join Our Mission to Make a Difference

The Human Dirofilariasis Research Institute (HDRI), is a 501(c)(3) nonprofit dedicated to raising awareness and conducting research on human occult heartworm disease. It seeks to break the cycle of suffering associated with this stealth disease by developing a clinical diagnostic tests and treatment protocols. The institute focuses on advocating for those affected by the disease, conducting necessary research, and creating innovative diagnostic tools to validate the existence and impact of Dirofilariasis.

We believe increased awareness can lead to more research, funding, and development of diagnostic tests and treatment protocols, ultimately benefiting those affected by the disease. Take a look at the personal stories and research in the Community and Science sections of this website to learn more.

In accordance with our mission, this website is divided into three sections focused on the three basic audiences that we serve.

Community – This section entry is devoted to those suffering from this disease. It is dedicated to helping these people find resources and exchange information on how to cope with this debilitating disease. These are the people we actually serve.

The Science – This menu is dedicated to the education of the general public presenting the largely unknown but crucial facts about this disease. Here you will find cross correlations among many scientific references that have never before been connected to provide important, overarching insight into this chronic disease.

HDRI Info – This is where you will find what HDRI.org as a 501(c)(3) organization is doing about this disease, as well as the background information of who we are, and any potential future research we are trying to fund.